Introduction
This book offers a multidisciplinary exploration of eutectic mixtures (EMs) as a strategy for overcoming poor aqueous solubility, dissolution and bioavailability of active pharmaceutical ingredients (APIs). Beginning with foundational pharmaceutical concepts, it progresses through the physicochemical, thermodynamic and solid-state fundamentals of EMs, their preparation and characterization, computational prediction of solubility behavior and applications across oral, topical, transdermal and advanced drug delivery systems.
Key Features
- - Comprehensive coverage from drug fundamentals to industrial applications of EMs.
- - Preparation methods: mechanical, solvent-assisted, fusion and innovative techniques.
- - Analytical and characterization tools (DSC, TGA, PXRD, FTIR, Raman spectroscopy, microscopy).
- - Computational approaches for predicting solubility and EM behavior.
- - Experimental evaluation of drug release, toxicity and safety.
- - Insights into drug coformer selection strategies.
Target Readership :
Undergraduates, postgraduates, research scholars and professors/researchers.
