Editors: Kai-Uwe Lewandrowski, Alexander Richard Vaccaro, Morgan P. Lorio, Paul Park, Rossano Kepler Alvim Fiorelli, Benedikt W. Burkhardt

Real World Evidence in Spine Surgery-2026 Update

Special Offer (PDF + Printed Copy): US $142
Printed Copy: US $142
ISBN: 979-8-89881-577-6 (Print)
ISBN: 979-8-89881-576-9 (Online)
Year of Publication: 2026
DOI: 10.2174/97988988157691260101

Introduction

Real World Evidence in Spine Surgery: 2026 Update provides real-world evidence that complements and refines findings from randomised controlled trials, systematic reviews, and meta-analyses in spine care. The book bridges evidence-based medicine with everyday clinical practice, highlighting how patient complexity, surgeon experience, and long-term outcomes influence treatment decisions beyond controlled study settings.

Using published literature, structured surgeon survey data, and Rasch-based analysis, the book provides a practical framework for understanding clinical effectiveness across diverse spine conditions and procedures. It covers key areas such as spinal biomechanics, degenerative disorders, neuromonitoring, implants, robotics, minimally invasive techniques, deformity, trauma, and outcome assessment, while comparing formal evidence with real-world surgical experience.


Key Features

  • - Integrates real-world evidence with clinical trial data.
  • - Covers major spine surgery domains and technologies.
  • - Comparative analysis of evidence vs. surgeon experience.
  • - Uses structured survey data and Rasch-based methodology to provide practical insights for clinical decision-making and research.

Target Readership :

Surgical fellows, residents, clinical researchers, healthcare administrators, and other professionals involved in spine care.

Contributors

Editor(s):
Kai-Uwe Lewandrowski
Center For Advanced Spine Care of Southern Arizona
University of Arizona
Tucson
AZ, USA


Alexander Richard Vaccaro
Sidney Kimmel Medical College at Thomas Jefferson University
Philadelphia
Pennsylvania
USA


Morgan P. Lorio
Advanced Orthopedics, 499 East Central Parkway
Altamonte Springs, FL 32701
Orlando College of Osteopathic Medicine
Winter Garden, FL, USA


Paul Park
Semmes-Murphey Department of Neurosurgery
University of Tennessee Health Sciences Center
Memphis Tennessee
USA


Rossano Kepler Alvim Fiorelli
Department of General and Specialized Surgery
Gaffrée e Guinle University Hospital
Federal University of the State of Rio de Janeiro
Rio de Janeiro - RJ
Brazil


Benedikt W. Burkhardt
Wirbelsäulenzentrum/Spine Center—WSC
Klinik Hirslanden
Witellikerstrasse 40, 8032 Zurich
Switzerland




Contributor(s):
Alexander R. Vaccaro
Department of Orthopaedic Surgery
Sidney Kimmel Medical College at Thomas Jefferson University and The Rothman Institute
Philadelphia, Pennsylvania
USA


Álvaro Dowling
Endoscopic Spine Clinic
USP, Ribeirão Preto
Santiago, Chile; Ribeirão Preto, Brazil
Chile; Brazil


Avelino Parajón
Department of Neurosurgery
Hospital Universitario Ramón y Cajal
Madrid
Spain


Benedikt W. Burkhardt
Wirbelsäulenzentrum/Spine Center—WSC
Hirslanden Klinik Zurich
Zurich
Switzerland


Christian Morgenstern
Morgenstern Institute of Spine
Teknon Medical Center
Barcelona
Spain


Emmanouil Liodakis
Department of Trauma, Hand and Reconstructive Surgery (Klinik für Unfall-, Hand- und Wiederherstellungschirurgie)
Saarland University Medical Center
Homburg
Germany


Hansjörg Leu
Wirbelsäulenzentrum/Spine Center—WSC
Hirslanden Klinik Zurich
Zurich
Switzerland


Hyeun-Sung Kim
Harrison Spinartus Hospital Chungdam
Seoul
South Korea


João Paulo Machado Bergamaschi
Atualli Spine Care Clinic
Alameda Santos, São Paulo
Brazil


Jorge Felipe Ramirez Leon
Minimally Invasive Spine Center; Reina Sofía Clinic; Fundación Universitaria Sanitas
Bogotá, D.C.
Colombia


Jun Ho Lee
Department of Neurosurgery
Wooridul Spine Hospital
Seoul, Republic of Korea
South Korea


Kai-Uwe Lewandrowski
Center for Advanced Spine Care of Southern Arizona
University of Arizona, Banner Medical Center; Fundación Universitaria Sanitas Bogotá; Hospital Universitário Gaffree Guinle, Universidade Federal do Estado do Rio de Janeiro
Tucson, Arizona, USA; Bogotá, D.C., Colombia; Rio de Janeiro, Brazil
USA


Malcolm Pestonji
Mahatma Gandhi Memorial University of Health Sciences
Navi Mumbai, Maharashtra
India


Matthew Scott-Young
Faculty of Health Science and Medicine
Bond University
Southport, Gold Coast, QLD
Australia


Morgan P. Lorio
Advanced Orthopedics
Orlando College of Osteopathic Medicine
Altamonte Springs / Winter Garden, FL
USA


Nicola Montemurro
Department of Neurosurgery
Azienda Ospedaliero Universitaria Pisana (AOUP), University of Pisa
Pisa
Italy


Oliver D. Fabrig
Hai Yan Lab
Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR)
Innovis
Singapore


Óscar Luis Alves
Head of Neurosurgery
Hospital Lusíadas Porto
Porto
Portugal


Paul Park
Semmes-Murphey Department of Neurosurgery
University of Tennessee Health Sciences Center
Memphis, Tennessee
USA


Rossano Kepler Alvim Fiorelli
Department of General and Specialized Surgery
Gaffrée e Guinle University Hospital, Federal University of the State of Rio de Janeiro (UNIRIO)
Rio de Janeiro
Brazil


Sergio Luis Schmidt
Department of Neurology
Federal University of the State of Rio de Janeiro (UNIRIO)
Rio de Janeiro
Brazil


Zhong-Liang Deng
Department of Orthopaedics
The Second Affiliated Hospital of Chongqing Medical University
Chongqing
China