Natural Language Processing in Healthcare Informatics: Challenges and Future Directions

Natural Language Processing in Healthcare Informatics: Challenges and Future Directions is an exploration into the transformative role of NLP and AI technologies in modern healthcare systems. The book delves into foundational concepts, advanced deep learning techniques, and cutting-edge applications of NLP in clinical decision support, electronic health record analysis, medical literature mining, patient-provider communication, and personalised medicine.

Structured across ten detailed chapters, the volume covers both theoretical foundations and practical implementations. Early chapters introduce AI and NLP in healthcare, highlighting applications in telehealth, wearable technologies, robotic surgery, and FDA-approved AI devices. Subsequent chapters examine challenges unique to healthcare NLP, including data quality and standardisation, linguistic variability, computational limitations, and ethical considerations such as bias, transparency, and patient privacy.

The book also provides in-depth insights into deep learning approaches for medical text analysis, preprocessing and annotation strategies, the evaluation of large language models for RNA interactions, and the application of Bi-LSTM architectures for advanced healthcare NLP tasks. Innovative chapters explore the role of knowledge graphs in rare disease prediction, AI and ML for focused ultrasound treatments, mathematical modelling using fuzzy numbers for healthcare NLP trends, and AI/ML integration in drug discovery and personalised medicine.

Key Features

- Detailed discussions and case studies on the applications of AI and NLP in healthcare, including telehealth, EHR analysis, and medical imaging.
- In-depth coverage of challenges in healthcare NLP encompassing data quality, linguistic variability, computational requirements, and ethical considerations.
- Explores deep learning techniques: RNNs, CNNs, Transformers, Bi-LSTM, and their application to medical text.
- Gives practical guidance on data preprocessing, annotation, and evaluation for healthcare NLP tasks.
- Provides insight into emerging trends by integrating theoretical concepts with real-world implementations, coding examples, and model workflows in Python and MATLAB.

Target Readership:

Researchers, students and specialised professionals in healthcare bioinformatics, computer science and biomedical engineering.

Editor(s):

A. Shankar
Department of ECE
Manakula Vinayagar Institute of Technology
Current Affiliation
Department of ECE
Hindusthan College of Engineering & Technology
Coimbatore
Puducherry
India

Saranya Jayapalan
Department of Bioinformatics
Pondicherry University
Puducherry
India

Basant. K. Tiwary
Department of Bioinformatics
Pondicherry University
Puducherry
India

Contributor(s):

A. Britto Manoj
Advanced Computer Science and Engineering
Vignan’s Foundation for Science, Technology, and Research
Vadlamudi (Post), Guntur (Dist.)
India

A. Shankar
Department of ECE
Manakula Vinayagar Institute of Technology
Puducherry
India

Arockiyajainmary Michealsamy
Independent Researcher
Chennai, Tamilnadu
India

Avantika Sharma
School of Life and Basic Sciences
Jaipur National University
Jaipur, Rajasthan
India

Balu Bhasuran
eHEALTH Lab, College of Communication and Information
Florida State University
TallahasseeFL, 32306-2100
USA

Basant K. Tiwary
Department of Bioinformatics
Pondicherry University
Puducherry
India

Bharath Addepalli
Department of Computing Technologies
SRM Institute of Science and Technology
Kattankulathur
India

Divyanshi Salundiya
School of Life and Basic Sciences
Jaipur National University
Jaipur, Rajasthan
India

Forhan Bin Emdad
eHEALTH Lab, College of Communication and Information
Florida State University
TallahasseeFL, 32306-2100
USA

Guneswar Sethi
Center for Companion Animal New Drug Development
Korea Institute of Toxicology, 30 Baehak 1-gil
Jeongeup, Jeollabuk-do - 56212
Republic of Korea

Gurusamy Murugesan
Department of Computer Science and Engineering
Koneru Lakshmaiah Education Foundation
Vaddeswaram, Guntur, Andhra Pradesh-522302
India

Jeong Ho Hwang
Center for Companion Animal New Drug Development
Korea Institute of Toxicology, 30 Baehak 1-gil
Jeongeup, Jeollabuk-do - 56212
Republic of Korea

Jeyakanthan Jeyaraman
Structural Biology and Biocomputing Lab, Department of Bioinformatics
Alagappa University
Karaikudi-630004, Tamil Nadu
India

Jeyaraman Jeyakanthan
Department of Bioinformatics (4th Floor), Science Block
Alagappa University
Karaikudi – 630003, Tamil Nadu
India

Jishnu K S
Department of Computing Technologies, School of Computing, CET
SRM Institute of Science and Technology, Kattankulathur Campus
Chennai, Tamil Nadu
India

Juhi Sharma
School of Life and Basic Sciences
Jaipur National University
Jaipur, Rajasthan
India

K P Naveen
Pondicherry Institute of Medical Sciences
Puducherry
India

K. Suresh Joseph
Department of Computer Science
Pondicherry University
Puducherry
India

Karthika Alagesan
Department of Bioinformatics (4th Floor), Science Block
Alagappa University
Karaikudi – 630003, Tamil Nadu
India

Kratika Pathak
School of Life and Basic Sciences
Jaipur National University
Jaipur, Rajasthan
India

L. Sankar Ganesh
School of Computer Science and Engineering
Vellore Institute of Technology
Vellore
India

Maharaja Muthuvairam Subbulakshmi
Structural Biology and Biocomputing Lab, Department of Bioinformatics
Alagappa University
Karaikudi-630004, Tamil Nadu
India

Manikandan Jayaraman
Structural Biology and Biocomputing Lab, Department of Bioinformatics
Alagappa University
Karaikudi-630004, Tamil Nadu
India

MK Bhanuja
Department of Computer Science
Pondicherry University
Puducherry
India

Mohammad Ishtiaque Rahman
Department of Information Systems
University of Maryland - Baltimore County

USA

P. Mohan Kumar
School of Computer Science and Engineering
Vellore Institute of Technology
Vellore
India

P.M. Benson Mansingh
Advanced Computer Science and Engineering
Vignan’s Foundation for Science, Technology, and Research
Vadlamudi (Post), Guntur (Dist.)
India

Pradeep Kumar Sriram
Structural Biology and Biocomputing Lab, Department of Bioinformatics
Alagappa University
Karaikudi-630004, Tamil Nadu
India

R Brindha
Department of Computing Technologies, School of Computing, CET
SRM Institute of Science and Technology, Kattankulathur Campus
Chennai, Tamil Nadu
India

R K Pongiannan
Department of Computing Technologies, School of Computing, CET
SRM Institute of Science and Technology, Kattankulathur Campus
Chennai, Tamil Nadu
India

R. Brindha
Department of Computing Technologies
SRM Institute of Science and Technology
Kattankulathur
India

R. Deepalakshmi
Department of ECE
CARE College of Engineering
Tiruchirappalli, Tamil Nadu
India

R. Elanthirayan
Department of Electrical and Electronics Engineering
St. Joseph College of Engineering
Chennai, Tamil Nadu-600119
India

R. Sofia
Department of Electronics and Communication Engineering
Manakula Vinayagar Institute of Technology
Puducherry
India

Raji Rajmichael
Department of Bioinformatics (4th Floor), Science Block
Alagappa University
Karaikudi – 630003, Tamil Nadu
India

S. Mary Praveena
Department of ECE
Sri Ramakrishna Institute of Technology
Coimbatore
India

S. Yazhinian
Department of Computer Science
Vel Tech Rangarajan Dr. Sagunthala R&D Institute of Science & Technology
Chennai
India

Sabenabanu Abdulkadhar
Department of Computer Science and Engineering; Department of Computer Applications, Faculty of Science and Humanities
Koneru Lakshmaiah Education Foundation; SRM Institute of Science and Technology, Kattankulathur
Vaddeswaram, Guntur, Andhra Pradesh-522302; Chennai-603203, Tamil Nadu
India

Saranya Jayapalan
Department of Bioinformatics
Pondicherry University
Puducherry
India

Shijukumar K
Department of Computing Technologies, School of Computing, CET
SRM Institute of Science and Technology, Kattankulathur Campus
Chennai, Tamil Nadu
India

Sneha Subramaniyan
Department of Bioinformatics (4th Floor), Science Block
Alagappa University
Karaikudi – 630003, Tamil Nadu
India

Sumit Govil
School of Life and Basic Sciences
Jaipur National University
Jaipur, Rajasthan
India

T Sayamsmruti Panda
BRIC- Institute of Life Sciences
Bhubaneswar, Odisha
India

Tamilalagan S
Department of Computing Technologies, School of Computing, CET
SRM Institute of Science and Technology, Kattankulathur Campus
Chennai, Tamil Nadu
India

Uzma Patel
School of Life and Basic Sciences
Jaipur National University
Jaipur, Rajasthan
India

Veerapandiyan Malaisamy
Department of Bioinformatics (4th Floor), Science Block
Alagappa University
Karaikudi – 630003, Tamil Nadu
India

Yasmin Abdulkadhar
Department of Artificial Intelligence and Data Science
Excel Engineering College (Autonomous)
Pallakapalayam, Namakkal, Tamil Nadu-637303
India

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