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Unravelling Alzheimer’s: Innovations in Pathogenesis, Diagnosis, and Therapeutics

Editors: Prashant Kumar Dhakad, Raghav Mishra, Shweta Sharma, Sudhanshu Mishra, Nishant Gaur

Unravelling Alzheimer’s: Innovations in Pathogenesis, Diagnosis, and Therapeutics

ISBN: 979-8-89881-496-0
eISBN: 979-8-89881-495-3 (Online)

Introduction

Unravelling Alzheimer’s: Innovations in Pathogenesis, Diagnosis, and Therapeutics provides a comprehensive and multidisciplinary exploration of Alzheimer’s Disease (AD), one of the most pressing neurodegenerative disorders of our time.

The book examines the historical evolution, epidemiology and global impact of AD, followed by an in-depth discussion on molecular and cellular mechanisms, including amyloid-beta aggregation, tau pathology, neuroinflammation, oxidative stress, and genetic factors. It highlights advances in biomarker discovery and early detection strategies, alongside cutting-edge diagnostic technologies such as neuroimaging and AI-driven tools. Case studies and patent insights further bridge research innovation with real-world clinical application.


Key Features

  • - Comprehensive coverage of Alzheimer’s disease pathogenesis and molecular mechanisms.
  • - Detailed analysis of biomarkers for early detection and therapeutic targeting.
  • - Exploration of advanced diagnostic technologies and pharmacological advancements, including innovative drug delivery systems, neuroimaging technologies and AI-based tools.
  • - In-depth discussion on novel therapies such as immunotherapy, gene therapy, RNA-based treatments, and natural compounds.
  • - Case studies and recent developments linking research to clinical practice.
  • - Integrated perspectives combining neuroscience, pharmacology, biotechnology, and clinical medicine.

Target Readership:

Clinicians, pharmaceutical scientists, healthcare professionals, R&D specialists, and industry practitioners working in neurodegenerative disease research and drug development.

Foreword

Unravelling Alzheimer’s: Innovations in Pathogenesis, Diagnosis, and Therapeutics

Alzheimer’s disease stands as one of the most formidable challenges to global health in the 21st century. As populations age and life expectancy increases, the burden of neurodegenerative diseases, particularly Alzheimer’s, has grown exponentially, touching countless lives and posing significant emotional, social, and economic tolls. The urgency to understand, diagnose, and treat this devastating disorder has never been more critical.

It is against this backdrop that Unravelling Alzheimer’s: Innovations in Pathogenesis, Diagnosis, and Therapeutics emerges as a timely and impactful scholarly contribution. Edited by Mr. Sudhanshu Mishra and Dr. Raghav Mishra, along with a dedicated team of experts, this volume brings together a diverse and interdisciplinary exploration of the many facets of Alzheimer’s disease from its complex pathogenesis to state-of-the-art diagnostic approaches, and from natural therapeutics to gene and immunotherapy innovations.

The book thoughtfully integrates traditional knowledge and cutting-edge science. It explores the potential of natural compounds and phytochemicals while simultaneously embracing the future of diagnostics through artificial intelligence, neuroimaging, and biomarker discovery. The inclusion of gene therapy, RNA-based solutions, and emerging pharmacological treatments reflects the depth and foresight of the contributors. Equally valuable are the discussions surrounding comorbidities, intranasal drug delivery systems, and real-world insights gleaned from patents and case studies.

I commend the editors and contributors for their vision, dedication, and scholarly excellence in assembling this important body of work. This book is not just a repository of knowledge; it is a call to action for deeper inquiry, innovation, and hope in the fight against Alzheimer’s disease.

Vandana Arora Sethi
Lloyd Institute of Management and Technology,
Greater Noida, Uttar Pradesh 201306, India