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Quinones: A Privileged Moiety for Drug Discovery
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Editors: Ashutosh Kumar Dash, Deepak Kumar

Quinones: A Privileged Moiety for Drug Discovery

eBook: US $79 Special Offer (PDF + Printed Copy): US $127
Printed Copy: US $87
Library License: US $316
ISBN: 979-8-89881-028-3 (Print)
ISBN: 979-8-89881-027-6 (Online)
Year of Publication: 2025
DOI: 10.2174/97988988102761250101
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Introduction

A multidisciplinary exploration of quinones as a vital structural class in medicinal chemistry Drawing from both natural and synthetic sources, the book explores the structural diversity, reactivity, and therapeutic potential of quinone compounds, positioning them as privileged moieties in the development of pharmacologically active agents.

The text covers essential themes such as synthesis strategies, identification techniques, biochemical relevance, and pharmacodynamics of quinones and their derivatives. It delves into their traditional use in medicine, contemporary roles in treating diseases like cancer and infections, and their capacity to interact with multiple biological targets. Specific chapters discuss glyco hybrids, ROS generation, enzymatic pathways, and toxicity profiles, offering a comprehensive overview of their medicinal versatility.

Key Features:

  • - Explores synthesis and structural modification techniques
  • - Analyzes biochemical and pharmacodynamic mechanisms
  • - Reviews traditional and modern therapeutic uses
  • - Examines toxicity concerns and safety profiles
  • - Highlights marketed drugs and emerging candidates
  • - Presents recent studies and future trends


Readership:

Students, researchers, and professionals engaged in medicinal chemistry, pharmacology, and natural product research.


eBook: US $79 Special Offer: US $127 Printed Copy: US $87 Library License: US $316

Contributors

Editor(s):
Ashutosh Kumar Dash
R & D, Drug Discovery Division
Macleods Pharmaceuticals
India


Deepak Kumar
Department of Pharmaceutical Chemistry
School of Pharmaceutical Sciences
Shoolini University
Solan-173229, Himachal Pradesh
India



Contributor(s):
Adil Ali
Department of Biotechnology
Parul Institute of Applied Sciences and Research and Development Cell
Parul University, Vadodara 391760
Gujarat-India


Ankit Paul
Department of Biotechnology
Parul Institute of Applied Sciences and Research and Development Cell
Parul University, Vadodara 391760
Gujarat-India


Ashutosh Kumar Dash
Senior Research Scientist (R&D)
Drug Discovery Division, Macleod Pharmaceuticals Ltd
Mumbai
India


Deepak Kumar
Department of Pharmaceutical Chemistry
School of Pharmaceutical Sciences, Shoolini University
Solan-173229, Himachal Pradesh
India


Divyani P. Patel
Department of Chemistry, Government College Daman (Affiliated to Veer Narmad South Gujarat University, Surat)
Daman, U.T. of Dadra & Nagar Haveli and Daman & Diu
Gujarat 395007
India


Hiyashree Sharmah
Department of Pharmaceutical Chemistry, NETES Institute of Pharmaceutical Science (NIPS)
Nemcare Group of Institution
Mirza, Kamrup Assam 781125
India


Lokman Ali Ahmed
Department of Pharmaceutical Chemistry, NETES Institute of Pharmaceutical Science (NIPS)
Nemcare Group of Institution
Mirza, Kamrup Assam 781125
India


Mohd Hasan Mujahid
Department of Biotechnology
Parul Institute of Applied Sciences and Research and Development Cell
Parul University, Vadodara 391760
Gujarat-India


Priyanku Pradip Das
Department of Pharmaceutical Chemistry
School of Pharmaceutical Sciences, Shoolini University
Solan-173229, Himachal Pradesh
India


Ramesh Kumar
Department of Chemistry
Kurukshetra University Kurukshetra
Haryana 136119
India


Ram Sagar
Glycochemistry Laboratory
School of Physical Sciences, Jawaharlal Nehru University
New Delhi 110067
India


Rajendra Dighe
KBHSS Trust’s
Institute of Pharmacy
Malegaon, Maharashtra
India


Ritu Gilhotra
Gyan Vihar School of Pharmacy
Suresh Gyan Vihar University
Jaipur, Rajasthan
India


Satish Kumar Singh
Department of Chemistry, Government College Daman (Affiliated to Veer Narmad South Gujarat University, Surat)
Daman, U.T. of Dadra & Nagar Haveli and Daman & Diu
Gujarat 395007
India


Satyanarayana Battula
Department of Chemistry
Central University of Jammu, Jammu & Kashmir
181143
India


Shashikant Bhandari
AISSMS College of Pharmacy
Pune
Maharashtra
India


Suryakant R. Rode
Jai Research Foundation Valvada
Valsad
Gujrat
India


Santosh Kumar Rath
School of Pharmaceuticals and Population Health Informatics
Faculty of Pharmacy, DIT University, Dehradun
Uttarakhand-248009
India


Sunil Sharma
Glycochemistry Laboratory
School of Physical Sciences, Jawaharlal Nehru University
New Delhi 110067
India


Tarun Kumar Upadhyay
Department of Biotechnology
Parul Institute of Applied Sciences and Research and Development Cell
Parul University, Vadodara 391760
Gujarat-India


Vivek Vivek
Amity Institute of Click Chemistry Research and Studies
Amity University Uttar Pradesh
Noida 201313, UP
India


Yogesh Yadav
Glycochemistry Laboratory
School of Physical Sciences, Jawaharlal Nehru University
New Delhi 110067
India



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