Preface

The goal of this book is to give readers a basic understanding of the subject's practical components, from handling Zebrafish and mounting tissue to the practical effects of several significant and intricate experimental techniques.

These days, experimental pharmacology has greatly strayed from the traditional method to focus on molecular and biochemical issues. Experimental pharmacology has been enhanced and expanded by advances in the fields of electrophysiology, biochemistry, molecular biology, electronic or digital recording methods, and software. Owing to the government's strict rules (CPCSEA), obtaining animals for research is a difficult undertaking.

Zebrafish have gained popularity as a model organism in biomedical research. Recently, researchers have been trying to better understand and cure conditions including cancer and various genetic and neurological abnormalities. One of Zebrafish’s many benefits is that its embryo is transparent, making it possible to see how its tissues and organs grow and perform morphogenesis. This is crucial to comprehending the many systems that underlie health issues.

Some helpful elements of this book are available to the reader, such as the numerous worked-out examples that aid in putting theory into practice. A genuine effort was made to provide this book with as much pertinent material as possible, supporting it with appropriate examples and illustrated arguments. The subjects included in this book are carefully chosen in accordance with the majority of the contrived difficulties and the pharmacology curriculum. I believe this book will be useful to all recent graduates and postgraduates in the field of pharmacology, as well as to trainees and research personnel in their daily duties in allied health fields and toscientists in CROs with industrial drug development setups.

Several contemporary and straightforward experimental designs have been included to assist the students in their future drug discovery endeavors. Aside from this, the book covers a number of significant topics, including the ethics of using animals in experiments, how to handle and care for experimental animals, how to prepare solutions, and how to mount tissue for in vitro research.