Editors: Marcelina Párrizas, Rosa Gasa, Perla Kaliman

Epigenetics of Lifestyle

eBook: US $29 Special Offer (PDF + Printed Copy): US $133
Printed Copy: US $118
Library License: US $116
ISBN: 978-1-60805-534-0 (Print)
ISBN: 978-1-60805-299-8 (Online)
Year of Publication: 2012
DOI: 10.2174/97816080529981120101

Introduction

Recent advances in the fields of genomics and bioinformatics have made it increasingly clear that genetic sequence alone cannot explain how the genome regulates the development and function of complex multicellular organisms both in health and disease. This inference has led to the expansion of epigenetics as a discipline. Epigenetics refers to the way in which the environment in the wide sense participates in the regulation of gene expression. Several studies show that the well-known beneficial role of a healthy lifestyle over a number of pathologies or as a pre-emptive therapy is at least in part exerted through epigenetic mechanisms, thus giving rise to a new paradigm of preventive medicine based on the concept of genetic plasticity. In Epigenetics of Lifestyle, several contributors provide a comprehensive view of how various facets of lifestyle, including nutrition, exercise, stress, addiction or social interactions, affect chromatin (the combination of DNA and proteins that make up the contents of a cell nucleus) - resulting in profound and long-lasting changes in gene function. In summary, Epigenetics of Lifestyle is a fresh approach towards epigenetics and presents the reader with significant research findings in epigenetics and lifestyle studies. This volume is a simplified source of information for both undergraduate and working professionals interested in lifestyle medicine and life sciences in general.

Indexed in: Book Citation Index, Science Edition, Web of Science, BIOSIS Previews, Scopus, EBSCO.

Contributors

Editor(s):
Marcelina Párrizas
Laboratory of Diabetes and Obesity
Institut d’Investigacions Biomèdiques
August Pi i Sunyer (IDIBAPS) Barcelona
Spain


Rosa Gasa
Laboratory of Diabetes and Obesity
Institut d’Investigacions Biomèdiques
August Pi i Sunyer (IDIBAPS) Barcelona
Spain


Perla Kaliman
Neuroepigenetics Laboratory
Institut d’Investigacions Biomèdiques
August Pi i Sunyer (IDIBAPS) Barcelona
Spain




Contributor(s):
Bechara J. Saab
Brain Research Institute
University of Zürich and Swiss Federal Institute of Technology
Winterthurerstrasse 190
Zürich, CH-8057
Switzerland


Isabelle M. Mansuy
Brain Research Institute
University of Zürich and Swiss Federal Institute of Technology
Winterthurerstrasse 190
Zürich, CH-8057
Switzerland


Andrew Collins
Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology
Dorothy Hodgkin Building
University of Bristol
Whitson Street
Bristol
BS1 3NY
United Kingdom


María Gutièrrez-Mecinas
Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology
Dorothy Hodgkin Building
University of Bristol
Whitson Street
Bristol
BS1 3NY
United Kingdom


Alexandra F. Trollope
Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology
Dorothy Hodgkin Building
University of Bristol
Whitson Street
Bristol
BS1 3NY
UK


Johannes M.H.M. Reul
Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology
Dorothy Hodgkin Building
University of Bristol
Whitson Street
Bristol
BS1 3NY
United Kingdom


Carla Sanchis-Segura
Psychobiology section
Universitat Jaume I
Avda. Sos Baynat S/N
Castelló de la Plana, 12071
Spain


Marta Miquel
Psychobiology section
Universitat Jaume I
Avda. Sos Baynat S/N
Castelló de la Plana, 12071
Spain


Karen A. Lillycrop
Institute of Developmental Sciences
Mailpoint 887, Southampton General Hospital
Tremona Road
Southampton, So16 6YD
UK


Graham C. Burdge
2Human Development and Health
Faculty of Medicine
University of Southampton
Southampton
UK


Jorge A. Alegría-Torres
Departamento de Toxicologia Ambiental
Facultad de Medicina
Universidad Autonoma de San Luis Potosi
Mexico


Valentina Bollati
Department of Environmental and Occupational Health
Center of Molecular and Genetic Epidemiology
Università degli Studi di Milano and Fondazione IRCCS Ospedale Maggiore Policlinico
Mangiagalli e Regina Elena
Via San Barnaba 8
Milan, 20122
Italy


Andrea Baccarelli
Department of Environmental Health
Exposure, Epidemiology and Risk Program
Harvard School of Public Health
Boston
Massachusetts
USA




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